Re-targetable tools and methodologies for the efficient deployment of high-level source code on coarse-grained dynamically reconfigurable architectures

Reconfigurable computing traditionally consists of a data path machine (such as an FPGA) acting as a co-processor to a conventional microprocessor. This involves partitioning the application such that the data path intensive parts are implemented on the reconfigurable fabric, and the control flow intensive parts are implemented on the microprocessor. Often the two parts have to be written in different languages. New highly parallel data path architectures allow parallelism approaching that of FPGAs, but are able to be reconfigured very rapidly. As a result, it is possible to use these architectures to perform control flow in a manner similar to a microprocessor, and thus a complete program can be described from an unmodified high-level language (in particular C). This overcomes the historical instruction-level parallelism (ILP) wall.To make full use of the available parallelism , existing microprocessor tool flows are insufficient. Data path machines are typically programmed via HDL tools from the ASIC design world. This expresses algorithm s at a low er level than the application algorithm s are typically developed in. The work in this thesis builds upon earlier work to allow applications to be described from high-level languages, by employing low-level optimisations in the compiler back-end and working from the assembly, to maximise parallel efficiency. This consists of scheduling, where known techniques are used to pack instructions into basic blocks that map well to the reconfigurable core (optimising spatial efficiency); then automatic pipelining is applied to dramatically improve the achievable throughput (optimising temporal efficiency). Together these can be thought of as “instruction-level parallelism done right”. Speed-ups of more than an order of magnitude were achieved, yielding throughputs of 180-380M Pixels/s on typical image signal processing tasks, matching the performance of hard-wired ASICs.Furthermore, conventional software-based simulation technologies for data path machines are too slow for use in application verification. This thesis demonstrates how a high-speed software emulator can be created for self-controlled dynamically reconfigurable data path machines, using a static serialisation of the data paths in each configuration context. This yields run-time performance several orders of magnitude higher than existing techniques, making it suitable for use in feedback-directed optimisation

Safety of hospital discharge before return of bowel function after elective colorectal surgery

Background: Ileus is common after colorectal surgery and is associated with an increased risk of postoperative complications. Identifying features of normal bowel recovery and the appropriateness for hospital discharge is challenging. This study explored the safety of hospital discharge before the return of bowel function. Methods: A prospective, multicentre cohort study was undertaken across an international collaborative network. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The main outcome of interest was readmission to hospital within 30 days of surgery. The impact of discharge timing according to the return of bowel function was explored using multivariable regression analysis. Other outcomes were postoperative complications within 30 days of surgery, measured using the Clavien\u2013Dindo classification system. Results: A total of 3288 patients were included in the analysis, of whom 301 (9\ub72 per cent) were discharged before the return of bowel function. The median duration of hospital stay for patients discharged before and after return of bowel function was 5 (i.q.r. 4\u20137) and 7 (6\u20138) days respectively (P < 0\ub7001). There were no significant differences in rates of readmission between these groups (6\ub76 versus 8\ub70 per cent; P = 0\ub7499), and this remained the case after multivariable adjustment for baseline differences (odds ratio 0\ub790, 95 per cent c.i. 0\ub755 to 1\ub746; P = 0\ub7659). Rates of postoperative complications were also similar in those discharged before versus after return of bowel function (minor: 34\ub77 versus 39\ub75 per cent; major 3\ub73 versus 3\ub74 per cent; P = 0\ub7110). Conclusion: Discharge before return of bowel function after elective colorectal surgery appears to be safe in appropriately selected patients

Safety of hospital discharge before return of bowel function after elective colorectal surgery

© 2020 BJS Society Ltd Published by John Wiley & Sons LtdBackground: Ileus is common after colorectal surgery and is associated with an increased risk of postoperative complications. Identifying features of normal bowel recovery and the appropriateness for hospital discharge is challenging. This study explored the safety of hospital discharge before the return of bowel function. Methods: A prospective, multicentre cohort study was undertaken across an international collaborative network. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The main outcome of interest was readmission to hospital within 30 days of surgery. The impact of discharge timing according to the return of bowel function was explored using multivariable regression analysis. Other outcomes were postoperative complications within 30 days of surgery, measured using the Clavien–Dindo classification system. Results: A total of 3288 patients were included in the analysis, of whom 301 (9·2 per cent) were discharged before the return of bowel function. The median duration of hospital stay for patients discharged before and after return of bowel function was 5 (i.q.r. 4–7) and 7 (6–8) days respectively (P < 0·001). There were no significant differences in rates of readmission between these groups (6·6 versus 8·0 per cent; P = 0·499), and this remained the case after multivariable adjustment for baseline differences (odds ratio 0·90, 95 per cent c.i. 0·55 to 1·46; P = 0·659). Rates of postoperative complications were also similar in those discharged before versus after return of bowel function (minor: 34·7 versus 39·5 per cent; major 3·3 versus 3·4 per cent; P = 0·110). Conclusion: Discharge before return of bowel function after elective colorectal surgery appears to be safe in appropriately selected patients